We're to live with the goal of the kingdom in mind. The kingdom of God come in Jesus has the goal of new creation, what Tom Wright has called "the new creation project". This project is to be carried on by all of us in Jesus, together and in our individual lives. It concerns everything, little and big. Some will be Pauls and Priscillas in their work. Others will serve behind the scenes, doing work that needs done. And all of us will be endeavoring to do so to the glory of God.
It's important to keep our eyes on the goal of the kingdom. This will help us keep things in good perspective. What matters in the end is to work towards what inevitably is to come in Jesus: the new creation and the kingdom of God which begin now, and are to be "consummated" when Christ returns. The smaller issues and lesser problems are also then put in their place. And the vision God can be giving us can become redemptive towards those troubling areas or problems in our lives.
I know this suffers from being overly general. Specifics are encouraged in whatever you might like to share here.